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Interfacing the nanostructured biosilica microshells of the marine diatom Coscinodiscus wailesii with biological matter

Paper ID Volume ID Publish Year Pages File Format Full-Text
1977 96 2008 5 PDF Available
Title
Interfacing the nanostructured biosilica microshells of the marine diatom Coscinodiscus wailesii with biological matter
Abstract

Biosilicified nanostructured microshells from the marine diatom Coscinodiscus wailesii have been properly functionalised to bind a molecular probe which specifically recognises a target analyte. The chemical modification process has been characterised by Fourier transformed infrared spectroscopy. Fluorescence measurements demonstrate that the antibodies we used, even if linked to the amorphous silica surface of C. wailesii microshells, still efficiently recognise their antigens. These low cost and largely available natural materials can be thus used as transducers elements for optical biosensors or as targeting microcapsules for drug delivery.

Keywords
Biosensors; Diatoms; Antibodies
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Interfacing the nanostructured biosilica microshells of the marine diatom Coscinodiscus wailesii with biological matter
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 4, Issue 1, January 2008, Pages 126–130
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us