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Web application for genetic modification flux with database to estimate metabolic fluxes of genetic mutants

Paper ID Volume ID Publish Year Pages File Format Full-Text
19988 43151 2016 6 PDF Available
Title
Web application for genetic modification flux with database to estimate metabolic fluxes of genetic mutants
Abstract

Computational analysis of metabolic fluxes is essential in understanding the structure and function of a metabolic network and in rationally designing genetically modified mutants for an engineering purpose. We had presented the genetic modification flux (GMF) that predicts the flux distribution of a broad range of genetically modified mutants. To enhance the feasibility and usability of GMF, we have developed a web application with a metabolic network database to predict a flux distribution of genetically modified mutants. One hundred and twelve data sets of Escherichia coli, Corynebacterium glutamicum, Saccharomyces cerevisiae, and Chinese hamster ovary were registered as standard models.

Keywords
Systems biology; Metabolic flux analysis; Elementary mode; Metabolic flux estimation; Genetic mutant database; Metabolic network data; Flux mutant prediction; Genetic modification
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Web application for genetic modification flux with database to estimate metabolic fluxes of genetic mutants
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 122, Issue 1, July 2016, Pages 111–116
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us