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Vessel network formation in response to intermittent hypoxia is frequency dependent

Paper ID Volume ID Publish Year Pages File Format Full-Text
20200 43162 2015 4 PDF Available
Title
Vessel network formation in response to intermittent hypoxia is frequency dependent
Abstract

A combined experimental and mathematical model of intermittent hypoxia (IH) conditioned engineered tissue was used to characterize the effects of IH on the formation of in vitro vascular networks. Results showed that the frequency of hypoxic oscillations has pronounced influence on the vascular response of endothelial cells and fibroblasts.

Keywords
Endothelial cells; Vasculogenesis; Oxygen; Intermittent hypoxia; 3D culture; Vascular endothelial growth factor
First Page Preview
Vessel network formation in response to intermittent hypoxia is frequency dependent
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 120, Issue 3, September 2015, Pages 347–350
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering