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Chemico-physical characterization of gelatin films modified with oxidized alginate

Paper ID Volume ID Publish Year Pages File Format Full-Text
2049 99 2010 6 PDF Available
Title
Chemico-physical characterization of gelatin films modified with oxidized alginate
Abstract

The possibility of using low concentrations of dialdehyde alginate (ADA) to crosslink and stabilize gelatin films was investigated. The films were prepared from gelatin solutions at different concentrations (5, 10 and 15 wt.%) containing different amounts of oxidized alginate (0, 1 and 3 wt.% with respect to the weight of gelatin). The extent of crosslinking increases as a function of ADA concentration, up to about 23%. The presence of oxidized alginate provokes a significant reduction in the degree of swelling and of gelatin release in phosphate-buffered saline solution, enhancing the effect of gelatin concentration. Furthermore, the values of the Young’s modulus, E, and of the stress at break, σb, increase with increasing ADA concentration. The observed small, but appreciable, increase in thermal stability found by differential scanning calorimetric investigation is supported by X-ray diffraction results.

Keywords
Gelatin; Alginate; Crosslinking; Mechanical properties; Swelling
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Chemico-physical characterization of gelatin films modified with oxidized alginate
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 2, February 2010, Pages 383–388
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
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Price was $35.95
You save - $31
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