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Biotransformation of 14-deoxy-14-methylenetriptolide into a novel hydroxylation product by Neurospora crassa

Paper ID Volume ID Publish Year Pages File Format Full-Text
20621 43183 2013 4 PDF Available
Title
Biotransformation of 14-deoxy-14-methylenetriptolide into a novel hydroxylation product by Neurospora crassa
Abstract

The biotransformation of 14-deoxy-14-methylenetriptolide by Neurospora crassa CGMCC AS 3.1604 to produce a new hydroxylation derivative was studied. The structure of this novel compound was determined using spectral data. This biotransformation using whole cells conditioned for 4 days transformed approximately 65% (mol ratio) of the substrate into the compound (5R)-5-hydroxy-14-deoxy-14-methylenetriptolide.

Keywords
Biotransformation; Neurospora crassa; Hydroxylation; Triptonide; 14-Deoxy-14-methylenetriptolide; (5R)-5-Hydroxy-14-deoxy-14-methylenetriptolide
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Biotransformation of 14-deoxy-14-methylenetriptolide into a novel hydroxylation product by Neurospora crassa
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 116, Issue 2, August 2013, Pages 199–202
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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