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Surface modification of and selective protein attachment to a flexible microarray pattern using atmospheric plasma with a reactive gas

Paper ID Volume ID Publish Year Pages File Format Full-Text
2065 99 2010 7 PDF Available
Title
Surface modification of and selective protein attachment to a flexible microarray pattern using atmospheric plasma with a reactive gas
Abstract

The hydrophobic and hydrophilic properties of the surface of poly-ether sulfone (PES) films were controlled by an atmospheric pressure plasma (AP) treatment using reactive gases (Ar/H2 and Ar/O2). The surface properties of the Ar/H2 and Ar/O2 in series AP-treated PES films showed higher surface roughness (∼120%), surface energy (∼30%) and hydrophilic properties (oxygen content ∼10%) than the Ar/O2 AP-treated PES film. The protein staining results confirmed that an activated region on the patterned PES film with high selectivity and sensitivity was well-defined and formed. This method is suitable for fabricating flexible protein adhesive chips with uniform biomolecular adhesive properties.

Keywords
Biocompatibility; Hydrophilicity; Micropatterning; Surface modification; Plasma
First Page Preview
Surface modification of and selective protein attachment to a flexible microarray pattern using atmospheric plasma with a reactive gas
Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 2, February 2010, Pages 519–525
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering