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Production of small nano-sized particles by complex formation between polycations and linearized plasmid DNA at a low pH

Paper ID Volume ID Publish Year Pages File Format Full-Text
20673 43185 2013 4 PDF Available
Title
Production of small nano-sized particles by complex formation between polycations and linearized plasmid DNA at a low pH
Abstract

We report on the technical advance of linearized pDNA (pDNAlinear) above the circular one (pDNAcirc) for preparation of small-sized DNA/polycation complexes (DPC) at a low pH. Also, the resistance of the DPC formed with pDNAlinear against poly-l-asparagine indicates that effective ion-pairing occurred between the pDNAlinear and polycations.

Keywords
Compaction; Polycation; Plasmid DNA; Linearized DNA; pH
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Production of small nano-sized particles by complex formation between polycations and linearized plasmid DNA at a low pH
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 116, Issue 4, October 2013, Pages 528–531
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us