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Microenvironment of alginate-based microcapsules for cell culture and tissue engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
20674 43186 2012 8 PDF Available
Title
Microenvironment of alginate-based microcapsules for cell culture and tissue engineering
Abstract

As a type of 3D model, the technology of microencapsulation holds significant promise for tissue engineering and cell therapy due to its unique performance. The microenvironmental factors within microcapsules play an important role in influencing the behaviors of encapsulated cells. The aim of this review article is to give an overview on the construction of the microenvironmental factors, which include 3D space, physicochemical properties of alginate matrix, cell spheroids, nutritional status, and so on. Furthermore, we clarified the effect of microenvironmental factors on the behaviors of encapsulated cells and the methods about improving the microenvironment of microcapsules. This review will help to understand the interaction of the microenvironment and the encapsulated cells and lay a solid foundation for microcapsule-based cell therapy and tissue engineering.

Keywords
Microcapsule; Microenvironment; Tissue engineering; Matrix stiffness; Cell spheroid
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Microenvironment of alginate-based microcapsules for cell culture and tissue engineering
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 114, Issue 1, July 2012, Pages 1–8
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us