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Current metabolomics: Practical applications

Paper ID Volume ID Publish Year Pages File Format Full-Text
20715 43188 2013 11 PDF Available
Title
Current metabolomics: Practical applications
Abstract

The field of metabolomics continues to grow rapidly over the last decade and has been proven to be a powerful technology in predicting and explaining complex phenotypes in diverse biological systems. Metabolomics complements other omics, such as transcriptomics and proteomics and since it is a ‘downstream’ result of gene expression, changes in the metabolome is considered to best reflect the activities of the cell at a functional level. Thus far, metabolomics might be the sole technology capable of detecting complex, biologically essential changes. As one of the omics technology, metabolomics has exciting applications in varied fields, including medical science, synthetic biology, medicine, and predictive modeling of plant, animal and microbial systems. In addition, integrated applications with genomics, transcriptomics, and proteomics provide greater understanding of global system biology. In this review, we discuss recent applications of metabolomics in microbiology, plant, animal, food, and medical science.

Keywords
Metabolomics; Metabolome; Mass spectrometry; Chemometrics; Multivariate analysis
First Page Preview
Current metabolomics: Practical applications
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 115, Issue 6, June 2013, Pages 579–589
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering