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Enhanced production of a self-toxic antibiotic xinghaiamine A from the novel marine-derived species Streptomyces xinghaiensis by resin addition

Paper ID Volume ID Publish Year Pages File Format Full-Text
20813 43192 2014 3 PDF Available
Title
Enhanced production of a self-toxic antibiotic xinghaiamine A from the novel marine-derived species Streptomyces xinghaiensis by resin addition
Abstract

An addition of 3% (w/v) adsorbent resin HP-20 at 3 days post-inoculation significantly improved xinghaiamine A production from 0.35 to 3.4 mg/L and shortened fermentation time from 18 to 9 days. Self-cytotoxicity of xinghaiamine A was verified and the minimal inhibitor concentration was estimated to be 8 μg/mL.

Keywords
Streptomyces xinghaiensis; Antibiotic production; Resin HP-20; Self-cytotoxic effects; Staphylococcus aureus
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Enhanced production of a self-toxic antibiotic xinghaiamine A from the novel marine-derived species Streptomyces xinghaiensis by resin addition
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 117, Issue 2, February 2014, Pages 200–202
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us