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Making headway in understanding pine wilt disease: What do we perceive in the postgenomic era?

Paper ID Volume ID Publish Year Pages File Format Full-Text
20842 43194 2013 8 PDF Available
Title
Making headway in understanding pine wilt disease: What do we perceive in the postgenomic era?
Abstract

The advent of next generation sequencing has revolutionized research approaches to biology by making entire genome sequences available and marking a new age in biology that has the potential to open innovative research avenues in various fields. Genome sequencing is now being applied in the fields of forest ecology and forest pathology, which previously had limited access to molecular techniques. One of the most advanced areas of progress is the study of “pine wilt disease”, which is caused by the parasitic nematode, Bursaphelenchus xylophilus. The entire genome sequence of B. xylophilus was determined in 2011, and since then, proteomic studies have been conducted to understand the molecular basis of the parasitism and pathogenicity of B. xylophilus. These postgenomic studies have provided numerous molecular insights and greatly changed our understanding of the pathogenesis of pine wilt disease. Here, we review the recent advances in genomic and proteomic approaches that address some of the longstanding questions behind the pathogenesis of pine wilt disease and have identified future questions and directions in this regard.

Keywords
Proteome; Genome; Bursaphelenchus xylophilus; Pine wood nematode; Parasite; Secreted protein; Surface coat protein; Evolution; Non-model organism; Forest pathology
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Making headway in understanding pine wilt disease: What do we perceive in the postgenomic era?
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 116, Issue 1, July 2013, Pages 1–8
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us