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Effect of preservation conditions of collagen substrate on its fibril formation and rabbit chondrocyte morphology

Paper ID Volume ID Publish Year Pages File Format Full-Text
21008 43201 2012 4 PDF Available
Title
Effect of preservation conditions of collagen substrate on its fibril formation and rabbit chondrocyte morphology
Abstract

The degree of collagen fibril formation was altered by varying the preservation conditions. The collagen substrate under atmosphere of nitrogen gas for 4 days exhibited well-developed collagen fibril network accompanied with the frequency of round-shaped chondrocyte cells (fR) of 0.62, the value of which was slightly lower than that on the reference substrate. The exposure to air and prolongation of preservation led to further degradation of collagen fibril networks accompanied with fR lower than 0.4. It was thus demonstrated that the preservation conditions of the collagen substrate influenced the chondrocyte cell morphology.

Keywords
Tissue engineering; Collagen type I coated substrate; Substrate preservation; Collagen fibril formation; Rabbit chondrocyte morphology
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Effect of preservation conditions of collagen substrate on its fibril formation and rabbit chondrocyte morphology
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 114, Issue 3, September 2012, Pages 360–363
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Full-text PDF Download
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Any Questions? feel free to contact us