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Techno-economic analysis of processes for Aspergillus carbonarius polygalacturonase production

Paper ID Volume ID Publish Year Pages File Format Full-Text
21148 43208 2012 7 PDF Available
Title
Techno-economic analysis of processes for Aspergillus carbonarius polygalacturonase production
Abstract

A techno-economic analysis of submerged (SmF) and solid state fermentation (SSF) processes for Aspergillus carbonarius polygalacturonase production was performed to make an appropriate process selection. The downstream processing involved integrated membrane process (IMP) and alginate affinity precipitation (AAP). For a production scale of 30 kL purified polygalacturonase concentrate per year, the total upstream cost of SmF was 14% lower than the SSF process. Downstream processing cost by IMP was 47% lower than AAP. The SmF-IMP process required a total capital investment that was 15–24% lower than the SmF-AAP and SSF-AAP processes. The corresponding unitary product cost was also lower by 24–36% in SmF-IMP process. Thus the SmF-IMP process proved to be very attractive from an economic point of view.

Keywords
Economic analysis; Aspergillus carbonarius; Polygalacturonase; Submerged fermentation; Solid-state fermentation; Integrated membrane process; Alginate affinity precipitation
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Techno-economic analysis of processes for Aspergillus carbonarius polygalacturonase production
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 113, Issue 5, May 2012, Pages 634–640
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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