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A two-scale model for simultaneous sintering and crystallization of glass–ceramic scaffolds for tissue engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
2123 100 2008 9 PDF Available
Title
A two-scale model for simultaneous sintering and crystallization of glass–ceramic scaffolds for tissue engineering
Abstract

Bioglass®-based glass–ceramic foams have been developed recently as highly porous, mechanically competent, bioactive and degradable scaffolds for bone tissue engineering. However, the development of the material so far has been based on a trial-and-error approach, and the existing materials are far from being optimized. In this paper, a mechanism-based model is presented for sintering deformation of Bioglass® foams. The porous foams consist of struts which, in turn, consist of Bioglass® particles. A corresponding two-scale model is developed based on existing viscous sintering models. Crystallization plays a key role in the sintering deformation of Bioglass® foams and is taken into account in the model. Qualitative comparison between the model predictions and experimental observations is presented, showing that the model is able to capture the complicated interplay between crystallization and viscous flow during the sintering process.

Keywords
Bioactive glass; Sintering; Crystallization; Model
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A two-scale model for simultaneous sintering and crystallization of glass–ceramic scaffolds for tissue engineering
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 4, Issue 4, July 2008, Pages 1095–1103
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us