Evolutionary adaptation of recombinant shochu yeast for improved xylose utilization
We examined the evolutionary adaptation of recombinant shochu yeast by serial anaerobic cultivation in xylose-based minimal medium. Compared with the parental strain, the adapted strain MA-S4-M1 (M1) markedly improved the growth on xylose and the anaerobic xylose consumption rate. M1 gained improved xylose utilization properties by optimizing the metabolic pathway enzymes and enhancing the uptake of xylose.
Journal: Journal of Bioscience and Bioengineering - Volume 110, Issue 1, July 2010, Pages 102–105