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Synthesis of phosphatidylinositols having various inositol stereoisomers by engineered phospholipase D

Paper ID Volume ID Publish Year Pages File Format Full-Text
21350 43218 2010 4 PDF Available
Title
Synthesis of phosphatidylinositols having various inositol stereoisomers by engineered phospholipase D
Abstract

Phospholipase D-mediated synthesis of phosphatidylinositols having various inositol stereoisomers was studied. Seven inositol stereoisomers were tested, all of which were found to be substrates of the enzyme, generating the corresponding phosphatidylinositols. Based on the substrate specificity, models for the recognition of inositol by the enzyme were proposed.

Keywords
Phosphatidylinositol; Inositol; Stereoisomer; Phospholipase D; Transphosphatidylation
First Page Preview
Synthesis of phosphatidylinositols having various inositol stereoisomers by engineered phospholipase D
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 109, Issue 4, April 2010, Pages 337–340
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering