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Phytochelatins inhibit the metal-induced aggregation of α-crystallin

Paper ID Volume ID Publish Year Pages File Format Full-Text
21425 43221 2009 4 PDF Available
Title
Phytochelatins inhibit the metal-induced aggregation of α-crystallin
Abstract

Phytochelatins (PCs) are heavy-metal-binding peptides found in some eukaryotes. This study investigates the use of plant-derived PCs for the inhibition of metal-induced protein aggregation. The results of this study show that PCs inhibit zinc-induced α-crystallin aggregation, and suggest that PCs might be useful as anti-cataract agents.

Keywords
Phytochelatins; Conformational disease; Cataracts; α-Crystallin; Heavy metal
First Page Preview
Phytochelatins inhibit the metal-induced aggregation of α-crystallin
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 107, Issue 2, February 2009, Pages 173–176
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering