Phytochelatins inhibit the metal-induced aggregation of α-crystallin
Phytochelatins (PCs) are heavy-metal-binding peptides found in some eukaryotes. This study investigates the use of plant-derived PCs for the inhibition of metal-induced protein aggregation. The results of this study show that PCs inhibit zinc-induced α-crystallin aggregation, and suggest that PCs might be useful as anti-cataract agents.
Journal: Journal of Bioscience and Bioengineering - Volume 107, Issue 2, February 2009, Pages 173–176