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Effects of insulator cHS4 on transgene expression from plasmid DNA in a positive feedback system

Paper ID Volume ID Publish Year Pages File Format Full-Text
21435 43222 2011 3 PDF Available
Title
Effects of insulator cHS4 on transgene expression from plasmid DNA in a positive feedback system
Abstract

The effects of a genetic insulator (chicken cHS4) on transgene expression in a positive feedback system using the GAL4-VP16 activator and luciferase reporter plasmids were examined. The introduction of cHS4 enhanced luciferase expression in mouse liver, indicating that this system would be useful for efficient transgene expression.

Keywords
Genetic insulator; cHS4; Plasmid; Positive feedback system; Transgene expression
First Page Preview
Effects of insulator cHS4 on transgene expression from plasmid DNA in a positive feedback system
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 112, Issue 5, November 2011, Pages 432–434
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering