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Biotransformation of quinazoline and phthalazine by Aspergillus niger

Paper ID Volume ID Publish Year Pages File Format Full-Text
21488 43224 2011 3 PDF Available
Title
Biotransformation of quinazoline and phthalazine by Aspergillus niger
Abstract

Cultures of Aspergillus niger NRRL-599 in fluid Sabouraud medium were grown with quinazoline and phthalazine for 7 days. Metabolites were purified by high-performance liquid chromatography and identified by mass spectrometry and proton nuclear magnetic resonance spectroscopy. Quinazoline was oxidized to 4-quinazolinone and 2,4-quinazolinedione, and phthalazine was oxidized to 1-phthalazinone.

Keywords
Aspergillus niger; Azaarene; Benzodiazine; Biotransformation; Phthalazine; Quinazoline
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Biotransformation of quinazoline and phthalazine by Aspergillus niger
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 111, Issue 3, March 2011, Pages 333–335
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us