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Lactobacillus-mediated RNA interference in nematode

Paper ID Volume ID Publish Year Pages File Format Full-Text
21642 43232 2010 4 PDF Available
Title
Lactobacillus-mediated RNA interference in nematode
Abstract

We engineered Lactobacillus paracasei to produce a dsRNA that would trigger RNAi-induced silencing of an essential gene in the nematode Caenorhabditis elegans. The dsRNA-expressing L. paracasei can be used in experiments conducted on culture plates and may also be used as an orally administrable dsRNA carrier for humans and other mammals.

Keywords
RNAi; dsRNA; Lactobacillus paracasei; Lactic acid bacteria; Caenorhabditis elegans; Nematode
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Lactobacillus-mediated RNA interference in nematode
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 109, Issue 2, February 2010, Pages 189–192
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us