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In vivo circular RNA production using a constitutive promoter for high-level expression

Paper ID Volume ID Publish Year Pages File Format Full-Text
21700 43235 2009 3 PDF Available
Title
In vivo circular RNA production using a constitutive promoter for high-level expression
Abstract

The permuted intron–exon (PIE) method based on group I intron self-splicing is the only methodology currently available for production of circular RNA in vivo. Here, we report improvement of the circular RNA expression method based on an induction-free vector system utilizing the highly efficient constitutive lpp promoter.

Keywords
Circularization; Permuted intron–exon; Aptamer; In vivo expression; Constitutive promoter
First Page Preview
In vivo circular RNA production using a constitutive promoter for high-level expression
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 108, Issue 4, October 2009, Pages 354–356
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering