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Computational fluid dynamics modeling of gas dispersion in multi impeller bioreactor

Paper ID Volume ID Publish Year Pages File Format Full-Text
21901 43242 2010 10 PDF Available
Title
Computational fluid dynamics modeling of gas dispersion in multi impeller bioreactor
Abstract

In the present study, experiments have been carried out to identify various flow regimes in a dual Rushton turbines stirred bioreactor for different gas flow rates and impeller speeds. The hydrodynamic parameters like fractional gas hold-up, power consumption and mixing time have been measured. A two fluid model along with MUSIG model to handle polydispersed gas flow has been implemented to predict the various flow regimes and hydrodynamic parameters in the dual turbines stirred bioreactor. The computational model has been mapped on commercial solver ANSYS CFX. The flow regimes predicted by numerical simulations are validated with the experimental results. The present model has successfully captured the flow regimes as observed during experiments. The measured gross flow characteristics like fractional gas hold-up, and mixing time have been compared with numerical simulations. Also the effect of gas flow rate and impeller speed on gas hold-up and power consumption have been investigated.

Keywords
Computational fluid dynamics (CFD); Multiphase flow; Bubble size; Gas dispersion; Mixing; Stirred tank
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 109, Issue 6, June 2010, Pages 588–597
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us