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Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups

Paper ID Volume ID Publish Year Pages File Format Full-Text
22007 43248 2008 4 PDF Available
Title
Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups
Abstract

Salidroside, a natural glycoside, was enzymatically derived for the first time into novel esters using lipase as biocatalyst. The reaction system of glycoside acylation was optimized, and the effect of solvent nature, concentrations of substrate and biocatalyst, and acyl donors' structure on the acylation was studied. In the optimal system, various structures of acyl donors, either natural or unnatural, including short alkyl acyl groups, long chain acyl groups and acyl donors with aryl group were connected to molecular backbone of the glycoside, forming various structures of novel glycoside esters.

Keywords
salidroside; salidroside ester; lipase; acylation; esterification; biocatalysis
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Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 106, Issue 1, July 2008, Pages 65–68
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us