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Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
2201 103 2007 8 PDF Available
Title
Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa ☆
Abstract

An adhesive protein extracted from marine mussels (Mytilus edulis) was used to bond strips of connective tissue for the purpose of evaluating the use of curing agents to improve adhesive curing. Specifically, mussel adhesive protein solution (MAPS, 0.5 mM dihydroxyphenylalanine) was applied, with or without the curing agents, to the ends of two overlapping strips of porcine small intestinal submucosa (SIS).The bond strength of this lap joint was determined after curing for 1 h at room temperature (25 °C). The strength of joints formed using only MAPS or with only the ethyl, butyl or octyl cyanoacrylate adhesives were determined. Although joints bonded using ethyl cyanoacrylate were strongest, those using MAPS were stronger than those using butyl and octyl cyanoacrylates. The addition of 25 mM solutions of the transition metal ions V5+, Fe3+ and Cr6+, which are all oxidants, increased the bond strength of the MAPS joints. The V5+ gave the strongest bonds and the Fe3+ the second strongest. In subsequent tests with V5+ and Fe3+ solutions, the bond strength increased with V5+ concentration, but it did not increase with Fe3+ concentration. Addition of 250 mM V5+ gave a very strong bond.

Keywords
Tissue adhesive; Porcine tissue; Small intestinal submucosa; Mussel adhesive protein; Metal ion
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Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 3, Issue 5, September 2007, Pages 687–694
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us