fulltext.study @t Gmail

Retroviral Gene Transduction into Chicken Embryo Gonads through Blood Circulation

Paper ID Volume ID Publish Year Pages File Format Full-Text
22048 43250 2008 4 PDF Available
Title
Retroviral Gene Transduction into Chicken Embryo Gonads through Blood Circulation
Abstract

A retroviral vector was injected into the heart of developing chicken embryos to determine the best timing for effective gene transduction into the gonads. Transduction efficiency and transgene expression were both highest when the viral solution was injected into embryos at stages 14–15 (Hamburger-Hamilton stages), in which primordial germ cells (PGCs) can be found in the blood circulation. This study shows that PGCs in the blood are important targets for gene transfer into the gonads using retroviral vectors.

Keywords
transgenic avian bioreactor; chicken embryo; retroviral vector; primordial germ cell; gonad
First Page Preview
Retroviral Gene Transduction into Chicken Embryo Gonads through Blood Circulation
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 106, Issue 6, December 2008, Pages 598–601
Authors
, , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us