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Effect of Static Pressure on Intracellular pH of Adhesive Chinese Hamster Ovary Cells

Paper ID Volume ID Publish Year Pages File Format Full-Text
22130 43255 2007 3 PDF Available
Title
Effect of Static Pressure on Intracellular pH of Adhesive Chinese Hamster Ovary Cells
Abstract

The effect of static pressure on the intracellular pH of the Chinese hamster ovary (CHO) cell line DR1000L4N was investigated. In cultivation of CHO cells at 0.9 MPa, two distinct populations were observed in the histogram of a flow cytometer, while single population was observed in cultivation at 0.1 MPa. The intracellular pH of the major population at 0.9 MPa was markedly lower than that of the single population at 0.1 MPa.

Keywords
static pressure; intracellular pH; Chinese hamster ovary cells
First Page Preview
Effect of Static Pressure on Intracellular pH of Adhesive Chinese Hamster Ovary Cells
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 104, Issue 6, December 2007, Pages 510–512
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering