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Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols

Paper ID Volume ID Publish Year Pages File Format Full-Text
22297 43267 2008 5 PDF Available
Title
Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols
Abstract

The object of this research was improvement of prenyl alcohol production with squalene synthase-deficient mutant Saccharomyces cerevisiae ATCC 64031. On screening of many kinds of additives, we found that oils and detergents significantly enhanced the extracellular production of prenyl alcohols. Soybean oil showed the most prominent effect among the additives tested. Its effect was accelerated by a high concentration of glucose in the medium. The combination of these cultivation conditions led to the production of more than 28 mg/l of farnesol in the soluble fraction of the broth. The addition of these compounds to the medium was an effective method for large-scale production of prenyl alcohols with microorganisms.

Keywords
farnesol; farnesyl diphosphate; geranyl geraniol; prenyl alcohol; terpenoid
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Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 106, Issue 3, September 2008, Pages 263–267
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us