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Novel Technique for Fabricating Double-Layered Tubular Constructs Consisting of Two Vascular Cell Types in Collagen Gels Used as Templates for Three-Dimensional Tissues

Paper ID Volume ID Publish Year Pages File Format Full-Text
22470 43288 2007 4 PDF Available
Title
Novel Technique for Fabricating Double-Layered Tubular Constructs Consisting of Two Vascular Cell Types in Collagen Gels Used as Templates for Three-Dimensional Tissues
Abstract

Double-layered tubular constructs consisting of two vascular cell types in collagen gels were fabricated using a previously developed technique [Takei et al., Biotechnol. Bioeng., 95, 1–7 (2006)]. Histological examination suggested that shear stress (4.0 dyn/cm2) on the luminal surface of the constructs induced morphological changes in their walls.

Keywords
tubular construct; vascular endothelial cell; vascular smooth muscle cell; collagen; tissue engineering
First Page Preview
Novel Technique for Fabricating Double-Layered Tubular Constructs Consisting of Two Vascular Cell Types in Collagen Gels Used as Templates for Three-Dimensional Tissues
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Bioscience and Bioengineering - Volume 104, Issue 5, 2007, Pages 435–438
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering