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Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: Experiments and modeling

Paper ID Volume ID Publish Year Pages File Format Full-Text
24227 43505 2010 11 PDF Available
Title
Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: Experiments and modeling
Abstract

Classically, information processing in the brain involves fast signaling mechanisms at a vast number of discrete sites, via spike-dependent neurotransmitter release at synapses. However, neurons also use a huge diversity of slower analog signaling mechanisms, these chemical signaling pathways, acting in a more global spatial scale and on a longer temporal scale, are closely related to social behaviors and emotion. How do these parallel signaling systems interact to give rise to coherent behavioral consequences? In this review, we consider the role of the neuropeptide oxytocin in the milk-ejection reflex as an example of how a complex neural network involving a peptidergic signaling pathway underlies the complex physiological behavior.

Keywords
Neuropeptide; Oxytocin; Vasopressin; Emergent bursting; Dendrites; Priming
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Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: Experiments and modeling
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Biotechnology - Volume 149, Issue 3, 1 September 2010, Pages 215–225
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us