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Selective laser sintering of hydroxyapatite/poly-ε-caprolactone scaffolds ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
2426 112 2010 7 PDF Available
Title
Selective laser sintering of hydroxyapatite/poly-ε-caprolactone scaffolds ☆
Abstract

Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and poly-ε-caprolactone, considered suitable for hard tissue engineering purposes, were used in a weight ratio of 30:70. The quality of the fabricated parts is influenced by various process parameters. Among them Four parameters, namely laser fill power, outline laser power, scan spacing and part orientation, were identified as important. These parameters were investigated according to a central composite design and a model of the effects of these parameters on the accuracy and mechanical properties of the fabricated parts was developed. The dimensions of the fabricated parts were strongly dependent on the manufacturing direction and scan spacing. Repeatability analysis shows that the fabricated features can be well reproduced. However, there were deviations from the nominal dimensions, with the features being larger than those designed. The compressive modulus and yield strength of the fabricated microstructures with a designed relative density of 0.33 varied between 0.6 and 2.3 and 0.1 and 0.6 MPa, respectively. The mechanical behavior was strongly dependent on the manufacturing direction.

Keywords
Selective laser sintering; Scaffold; Accuracy; Mechanical properties; Biodegradable
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Selective laser sintering of hydroxyapatite/poly-ε-caprolactone scaffolds ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 7, July 2010, Pages 2511–2517
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us