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Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media

Paper ID Volume ID Publish Year Pages File Format Full-Text
24478 43518 2010 4 PDF Available
Title
Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media
Abstract

Nitroalkanes underwent fast additions to a variety of structurally diverse aldehydes under the catalysis of d-aminoacylase in DMSO. The influences of reaction conditions including solvents, temperature, enzyme concentration and molar ratio of substrates were systematically investigated. Seventeen products were obtained in short time with moderate to high yields. It is the first report on hydrolase-catalyzed fast Henry reaction in organic solvent.

Keywords
Henry reaction; Nitroalkanes; Aldehyde; Hydrolase; β-Nitroalkanols
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Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Biotechnology - Volume 145, Issue 3, 1 February 2010, Pages 240–243
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us