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Influence of design on bioactivity of novel CaSiO3–CaMg(SiO3)2 bioceramics: In vitro simulated body fluid test and thermodynamic simulation

Paper ID Volume ID Publish Year Pages File Format Full-Text
2458 112 2010 11 PDF Available
Title
Influence of design on bioactivity of novel CaSiO3–CaMg(SiO3)2 bioceramics: In vitro simulated body fluid test and thermodynamic simulation
Abstract

A new type of bioactive ceramic has been designed and obtained from high-temperature phase information from the wollastonite (CaSiO3)–diopside (CaMg(SiO3)2) phase equilibrium diagram. The selected composition was that corresponding to the eutectic point of the pseudobinary CaSiO3–CaMg(SiO3)2 system. The sintering behaviour, phase evolution, microstructural changes and in vitro bioactivity of CaSiO3–CaMg(SiO3)2 eutectic bioceramics were analysed by differential thermal analysis, X-ray diffraction, field emission scanning electron microscopy (FE-SEM) and image analysis. A simulation of the dissolution properties of the different materials studied, in water as well as in simulated body fluid (SBF), was also carried out by thermodynamic calculations, with the purpose of understanding the in vitro results obtained. The results demonstrate that the CaMg(SiO3)2 is significantly less soluble than CaSiO3, developing an in situ porous structure (biomimetic porous bone material) with adequate biodegradation rate and stability strength when immersed in SBF. The influence of the microstructure (porosity, grain size and phase composition) on the in vitro bioactivity of the obtained bioceramics was also examined.

Keywords
Diopside; Wollastonite; Microstructure; Bioactivity; Thermodynamic simulation
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Influence of design on bioactivity of novel CaSiO3–CaMg(SiO3)2 bioceramics: In vitro simulated body fluid test and thermodynamic simulation
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 7, July 2010, Pages 2797–2807
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us