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Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate–tricalcium silicate composite bone cements

Paper ID Volume ID Publish Year Pages File Format Full-Text
2479 113 2007 9 PDF Available
Title
Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate–tricalcium silicate composite bone cements
Abstract

Self-setting biomaterials are widely used for tissue repair and regeneration. Calcium sulfate hemihydrate has been used for many years as a self-setting biomaterial due to its good setting properties. However, too fast a degradation rate and lack of bioactivity have limited its application in orthopaedic field. Herein, tricalcium silicate was introduced into calcium sulfate hemihydrate (CaSO4 · 1/2H2O) to form a calcium sulfate hemihydrate-based composite, and its behavior as a cement was studied in comparison with pure calcium sulfate hemihydrate. The results indicated that the workability and setting time of the composite pastes are higher than those of pure CaSO4 · 1/2H2O, and the composite pastes showed much better short- and long-term mechanical properties than those of pure CaSO4 · 1/2H2O. Moreover, the biphasic specimens showed significantly improved bioactivity and degradability compared with those of pure CaSO4 · 1/2H2O, indicating that the composite cements might have a significant clinical advantage over the traditional CaSO4 · 1/2H2O cement.

Keywords
Bone cement; Bioactivity; Composite; Cytotoxicity; Silicate
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Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate–tricalcium silicate composite bone cements
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 3, Issue 6, November 2007, Pages 952–960
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us