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Elemental composition, morphology and mechanical properties of calcified deposits obtained from abdominal aortic aneurysms

Paper ID Volume ID Publish Year Pages File Format Full-Text
2553 115 2006 6 PDF Available
Title
Elemental composition, morphology and mechanical properties of calcified deposits obtained from abdominal aortic aneurysms
Abstract

Calcified deposits exist in almost all abdominal aortic aneurysms (AAAs). The significant difference in stiffness between these hard deposits and the compliant arterial wall may result in local stress concentrations and increase the risk of aneurysm rupture. Calcium deposits may also complicate AAA repair by hindering the attachment of a graft or stent-graft to the arterial wall or cause vessel wall injury at the site of balloon dilation or vascular clamp placement. Knowledge of the composition and properties of calcified deposits helps in understanding the risks associated with their presence. This work presents results of elemental composition, microscopic morphology, and mechanical property measurements of human calcified deposits obtained from within AAAs. The elemental analyses indicate the deposits are composed primarily of calcium phosphate with other assorted constituents. Microscopy investigations show a variety of microstructures within the deposits. The mechanical property measurements indicate an average elastic modulus in the range of cortical bone and an average hardness similar to nickel and iron.

Keywords
Calcium deposit; Mechanical properties; Elemental analysis; Electron microscopy; Abdominal aortic aneurysm
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Elemental composition, morphology and mechanical properties of calcified deposits obtained from abdominal aortic aneurysms
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 2, Issue 5, September 2006, Pages 515–520
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us