fulltext.study @t Gmail

Development of simple media which allow investigations into the global regulation of chivosazol biosynthesis with Sorangium cellulosum So ce56

Paper ID Volume ID Publish Year Pages File Format Full-Text
25731 43594 2006 9 PDF Available
Title
Development of simple media which allow investigations into the global regulation of chivosazol biosynthesis with Sorangium cellulosum So ce56
Abstract

Media, completely different with respect to their complexity, were investigated for growth and secondary metabolism with Sorangium cellulosum strain So ce56. While technical substrates are best for metabolite production, these media are not suitable to study gene expressions. Free amino acids as present in soluble media based on peptones were found to inhibit polyketide biosynthesis. Therefore synthetic growth and production media were developed. Different nitrogen- and carbon sources as well as trace elements were studied with respect to growth and regulation of chivosazol biosynthesis. A simple defined medium with asparagine as nitrogen source, glucose as carbon source and zinc ions as essential trace element is proposed for future studies into secondary metabolism using transcriptomics and proteomics.

Keywords
Sorangium cellulosum; So ce56; Growth; Secondary metabolism; Chivosazol; Synthetic medium; Zinc ion; Glycine; Genome; Growth media
First Page Preview
Development of simple media which allow investigations into the global regulation of chivosazol biosynthesis with Sorangium cellulosum So ce56
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Biotechnology - Volume 121, Issue 2, 24 January 2006, Pages 192–200
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us