fulltext.study @t Gmail

Poly(propylene fumarate)/(calcium sulphate/β-tricalcium phosphate) composites: Preparation, characterization and in vitro degradation

Paper ID Volume ID Publish Year Pages File Format Full-Text
2604 118 2009 8 PDF Available
Title
Poly(propylene fumarate)/(calcium sulphate/β-tricalcium phosphate) composites: Preparation, characterization and in vitro degradation
Abstract

This study aimed to prepare a poly(propylene fumarate)/(calcium sulphate/β-tricalcium phosphate) (PPF/(CaSO4/β-TCP)) composite. We first examined the effects of varying the molecular weight of PPF and the N-vinyl pyrrolidinone (NVP) to PPF ratio on the maximum cross-linking temperature and the composite compressive strength and modulus. Then the in vitro biodegradation behaviour of PPF/(CaSO4/β-TCP) composites was investigated. The effects of varying the molecular weight of PPF, the NVP/PPF ratio and the CaSO4/β-TCP molar ratio on the weight loss and the composite compressive strength and modulus were examined. The cross-linking temperature, which increased with increasing molecular weight of PPF and NVP/PPF ratio, ranged from 41 to 43 °C for all formulations. The mechanical properties were increased by a decrease in the NVP/PPF ratio. For all formulations, the compressive strength values fell between 12 and 62 MPa, while the compressive modulus values fell between 290 and 1149 MPa. The weight loss decreased either with increasing molecular weight of PPF or with decreasing NVP/PPF ratio and CaSO4/β-TCP molar ratio during degradation. The compressive strength and modulus increased with decreasing NVP/PPF ratio or decreasing CaSO4/β-TCP ratio. The greatest weight loss over 6 weeks was 14.72%. For all formulations, the compressive modulus values fell between 57 and 712 MPa and the compressive strength fell between 0.5 and 21 MPa throughout 6 weeks degradation. Scanning electron microscopy and X-ray diffraction analysis of the PPF/(CaSO4/β-TCP) composites demonstrated that hydroxyapatite was deposited on the surface of CaSO4/β-TCP granules during degradation.

Keywords
Poly(propylene fumarate); Calcium sulphate/β-tricalcium phosphate; Preparation; Characterization; In vitro degradation
First Page Preview
Poly(propylene fumarate)/(calcium sulphate/β-tricalcium phosphate) composites: Preparation, characterization and in vitro degradation
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 5, Issue 2, February 2009, Pages 628–635
Authors
, , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us