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Sol–gel derived aluminosilicate coatings on alumina as substrate for osteoblasts

Paper ID Volume ID Publish Year Pages File Format Full-Text
2632 119 2006 10 PDF Available
Title
Sol–gel derived aluminosilicate coatings on alumina as substrate for osteoblasts
Abstract

Rat bone marrow stromal cell differentiation on aluminosilicate 3Al2O3–2SiO2 coatings was investigated. Thin ceramic coatings were prepared on α-alumina substrates by the sol–gel process and calcined in order to establish an amorphous aluminosilicate ceramic phase with and without nanosized transitional mullite crystals. In addition, coatings of thermally sprayed aluminosilicate and diphasic γ-alumina–silica nanosized colloids were prepared. Cell culture testing by rat osteoblasts showed good biocompatibility for aluminosilicates with sustained normal osteoblast functions. Despite mutual disparities in physical and chemical nanostructures, the culture findings suggested fairly similar osteoblast response to all tested coatings. The results suggest that topographical frequency parameters and chemical uniformity are important parameters in determining the best conditions for osteoblasts on sol–gel derived aluminosilicate materials.

Keywords
Aluminosilicate; Ceramic structure; Sol–gel techniques; Osteoblast; Cell culture
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 2, Issue 6, November 2006, Pages 659–668
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us