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Preparation of poly(lactic acid) composite hollow spheres containing calcium carbonates

Paper ID Volume ID Publish Year Pages File Format Full-Text
2661 122 2006 6 PDF Available
Title
Preparation of poly(lactic acid) composite hollow spheres containing calcium carbonates
Abstract

Poly(lactic acid) composite hollow spheres containing calcium carbonate were prepared by oil-in-water emulsion evaporation to develop injectable bone substitutes incorporated with cells. The spheres were ∼1.2 mm in diameter and had a shell with a thickness in the range of 50–150 μm. The hollow in the spheres was presumed to be formed by CO2 gas generated by the decomposition of vaterite used as a starting material. An open channel ∼800 μm in diameter was formed in the spheres by chemical etching utilizing the rapid dissolution of poly(lactic acid) at the thin portion of the shell. Cells could migrate into the hollow spheres through the open channel and attach to the inner surface.

Keywords
Poly(lactic acid); Calcium carbonate; Hollow sphere; Composite; Open channel
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Preparation of poly(lactic acid) composite hollow spheres containing calcium carbonates
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 2, Issue 4, July 2006, Pages 403–408
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us