Photophysical, photochemical and aggregation behavior of novel peripherally tetra-substituted phthalocyanine derivatives
In this study, the novel metal-free (4) and zinc (II) (5) phthalocyanine compounds substituted with four 1-(2-oxyethyl)-4-piperidone ethylene ketal functional groups at peripheral positions have been prepared. These new phthalocyanine compounds have been characterized by IR, 1H NMR, 13C NMR spectroscopy, MS spectral data and elemental analysis. The synthesized phthalocyanine compounds exhibited excellent solubility in common organic solvents and the zinc (II) phthalocyanine complex (5) showed J-type aggregation in chloroform. The photophysical and photochemical properties of metal-free (4) and zinc (II) (5) phthalocyanine complexes were also investigated in DMSO. The investigation of the photophysical and photochemical properties of photosensitizers is very useful for photodynamic therapy (PDT) applications.
► Synthesis and characterization of metal-free and zinc phthalocyanines.► Photophysical and photochemical properties in DMSO solution. ► Photodynamic therapy studies.
Journal: Journal of Photochemistry and Photobiology A: Chemistry - Volume 241, 1 August 2012, Pages 67–78