fulltext.study @t Gmail

Light induced oxidation of 2,3-dihydroquinazolin-4(1H)-ones

Paper ID Volume ID Publish Year Pages File Format Full-Text
27277 44014 2013 8 PDF Available
Title
Light induced oxidation of 2,3-dihydroquinazolin-4(1H)-ones
Abstract

•Photo-oxidation of 2-substituted 2,3-dihydroquinazolin-4(1H)-ones results in the formation of quinazolin-4(3H)-ones.•The electronic nature of the substituent on the 2-position and also the nature of solvent affect the rate of reaction.•An electron-transfer induced mechanism is proposed for this study.•Analysis of the computational results obtained at the DFT-B3LYP/6-31++G** level of theory supports this mechanism.

Light induced oxidation of various of 2-substituted 2,3-dihydroquinazolin-4(1H)-ones (DHQZs) results smoothly the formation of quinazolin-4(3H)-ones (QZs) product. The electronic nature of the substituent on the 2-position and also the nature of solvent affect the rate of reaction, which supports the proposed mechanism based on the electron-transfer induced photo-oxidation. Analysis of the computational results obtained at the DFT-B3LYP/6-31++G** level of theory supports the mechanism in which the first electron removal occurs preferably from the N1 atom of the heterocyclic ring. In contrast to the solution photochemistry, no changes have been observed by irradiation in the solid state.

Keywords
2,3-Dihydroquinazolin-4(1H)-one; Electron transfer; Photo-oxidation; Quinazolin-4(3H)-one
First Page Preview
Light induced oxidation of 2,3-dihydroquinazolin-4(1H)-ones
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology A: Chemistry - Volume 271, 1 November 2013, Pages 8–15
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us