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Robust and fluorescent silver nanoparticles using Artemisia annua: Biosynthesis, characterization and antibacterial activity

Paper ID Volume ID Publish Year Pages File Format Full-Text
2881 140 2015 7 PDF Available
Title
Robust and fluorescent silver nanoparticles using Artemisia annua: Biosynthesis, characterization and antibacterial activity
Abstract

•The fluorescent silver nanoparticles were synthesized using a medicinal plant leaf extract.•The synthesized nanoparticles are robust and biocompatible.•The nanoparticles show potent antibacterial activity against various bacterial strains.•The TEM analysis reveals that nanoparticles disrupt the bacterial cell membrane.

Metal nanoparticles have been studied extensively because of their unique physicochemical properties. Among the metal nanoparticles, silver nanoparticles have gained much interest over the last few years due to its good conductivity, chemical stability, catalytic and antimicrobial activity. In this study, fluorescent silver nanoparticles were synthesized using Artemisia annua leaf extract. After exposing the silver ions to the leaf extract, the rapid reduction of silver ions led to the formation of silver nanoparticles in solution. The synthesis was completed within 5 min. The synthesized fluorescent silver nanoparticles were characterized by UV–vis, fluorescence spectroscopy TEM, EDX, XRD, and FTIR. The antibacterial activity of the nanoparticles against gram negative and gram positive bacterial strains were studied. The antibacterial effect was studied by MIC and disk diffusion assay. The stability of fluorescent silver nanoparticles in biological media was demonstrated with the resistance to oxidation by the addition of H2O2. TEM analysis of fluorescent silver nanoparticles treated bacterial cells reveals that the silver nanoparticles exert antibacterial activity by disrupting the cell membrane structure and integrity. The biosynthesized silver nanoparticles were biocompatible which were confirmed by checking the cytotoxicity against human erythrocytes. The silver nanoparticles showed significant fluorescence and antibacterial activity, indicating that has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries.

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Keywords
Artemisia annua; Antibiotic; Biosynthesis; Cell disruption; Fluorescence; Microbial growth
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Robust and fluorescent silver nanoparticles using Artemisia annua: Biosynthesis, characterization and antibacterial activity
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 102, 15 October 2015, Pages 91–97
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us