Antibacterial behaviour of Vitex negundo extract assisted ZnO nanoparticles against pathogenic bacteria
•ZnO NPs originally synthesized by using Vitex negundo plant extract.•This is an eco-friendly synthesis at short time duration and without complicated procedures.•Polyphenolic compounds of Vitex negundo extract used as a hydrolytic agent.•Antibacterial activity of ZnO NPs was significant against bacterial pathogens.
The biological routes are advantageous over the chemical and physical ones as unlike. These, the biological synthesis protocol occurs at ambient conditions, are cheap, non-toxic and eco-friendly. This research describes the synthesis of zinc oxide nanoparticles (ZnO NPs) using Vitex negundo plant extract with zinc nitrate hexahydrate as precursor. Biomolecules present in plant extract can be used to hydrolyze metal ions into metal oxide NPs in a single-step green synthesis. The hydrolyzing agents involved the various water soluble plant metabolites such as flavonoid, alkaloids, flavone, phenolic compounds, terpenoids and co-enzymes. Presence of isoorientin (flavone) in V. negundo plant extract is mainly responsible for the formation of ZnO NPs. The prepared ZnO NPs were calcinated at 450 °C and were confirmed by XRD, FT-IR, UV–visible, SEM with EDX and DLS analysis. The biological application of antibacterial activity was done by gram positive and gram negative bacteria.
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Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 146, May 2015, Pages 52–57