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Trace metal ions in hair from frequent hair dyers in China and the associated effects on photo-oxidative damage

Paper ID Volume ID Publish Year Pages File Format Full-Text
29518 44416 2016 6 PDF Available
Title
Trace metal ions in hair from frequent hair dyers in China and the associated effects on photo-oxidative damage
Abstract

•Trace metals of iron and copper can accumulate in human hair with frequent dyeing.•Dyed hairs were shown to have increased protein oxidative modification levels.•A mechanism based on metal-catalyzed Fenton reaction is proposed.•Dyeing makes hair more susceptible to oxidative damage when exposed to UVA.

Human hairs are subject to oxidative modification when exposed to sunlight. In the present study, samples of human hair from Chinese volunteers that included frequent hair dyers and non-dyers were analyzed for metal ions such as iron, copper, magnesium, aluminum, zinc and lead. The generation of hydroxyl radicals during UVA (315–400 nm) photoageing was quantified and oxidative damages characterized by proteomic and SEM analysis. It was concluded that high levels of metal ions, particularly those derived from iron and copper, identified in the dyed hairs are associated with enhanced photoformation of hydroxyl radicals and resultant photooxidative damage of the hair. Reactive oxygen species, including hydroxyl radicals, generated via an electron transfer mechanism with hair photosensitizers react with hair proteins. Proteomic analysis of hair samples from frequent hair dyers, regardless of age and gender, showed an almost 1.6 fold increase in the protein oxidative modification levels compared to the undyed samples. As a result, a more pronounced physical damage including fragmentation and cross-linkage of cuticle scales was observed on the surface of dyed hair samples during the photoageing. This work is aimed at better understanding the role of metal ions in dyed hairs and their possible role in photosensitizing hair proteins. The results from this study are anticipated to contribute to the improved development of hair coloring cosmetics and hair care products.

Keywords
Human hair; Heavy metals; Hydroxyl radical; Proteomic analysis
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 156, March 2016, Pages 35–40
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us