fulltext.study @t Gmail

Effects of pulsed infra-red low level-laser irradiation on open skin wound healing of healthy and streptozotocin-induced diabetic rats by biomechanical evaluation

Paper ID Volume ID Publish Year Pages File Format Full-Text
29528 44419 2012 8 PDF Available
Title
Effects of pulsed infra-red low level-laser irradiation on open skin wound healing of healthy and streptozotocin-induced diabetic rats by biomechanical evaluation
Abstract

Diabetes is one of the most common causes of delayed wound healing. Low-level laser therapy (LLLT) are one of the therapeutic modalities used for the treatment of wounds. The aim of present study is to evaluate the effect of LLLT in experimentally-induced diabetic rats.Two full thickness skin incisions were made on dorsal regions of each rat. The wounds were randomly divided into laser-treated and placebo. Laser-treated wounds of the healthy (non-diabetic) animals were submitted to a pulsed-infrared 890 nm laser with an 80 Hz frequency and 0.03 J/cm2 for each wound point in the first healthy group and 0.2 J/cm2 in the second healthy group. Laser-treated wounds of the diabetic animals received the same pulsed-infrared laser treatments as the second group for each wound point. On day 15, a sample from each wound was extracted and submitted for tensile strength evaluation. Laser irradiation with 0.03 J/cm2 significantly decreased the maximum load for wound repair in healthy rats (p = 0.015). Laser irradiation with 0.2 J/cm2 significantly increased the maximum load in wounds from the healthy control (p = 0.021) and diabetic (p < 001) groups. Laser treatments with a pulsed infrared laser at 0.2 J/cm2 significantly accelerated wound healing in both healthy and diabetic rats.

► Diabetes is one of the most common causes of delayed wound healing. ► Low-level laser therapy (LLLT) is used for the treatment of wounds. ► We studied the effect of a pulsed laser on wound healing in diabetic rats. ► Healthy and diabetic rats were submitted to a laser with an 80 Hz frequency. ► LLLT at 0.2 J/cm2 accelerated wound healing in both healthy and diabetic rats.

Keywords
Infra-red laser; Low-level laser therapy; Diabetes; Skin; Wound healing process; Tensile strength
First Page Preview
Effects of pulsed infra-red low level-laser irradiation on open skin wound healing of healthy and streptozotocin-induced diabetic rats by biomechanical evaluation
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 111, 4 June 2012, Pages 1–8
Authors
, , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us