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The effect of red, green and blue lasers on healing of oral wounds in diabetic rats

Paper ID Volume ID Publish Year Pages File Format Full-Text
29711 44431 2015 4 PDF Available
Title
The effect of red, green and blue lasers on healing of oral wounds in diabetic rats
Abstract

•We compared the effects of red, green, and blue lasers in terms of accelerating oral wound healing in 32 diabetic rats.•We observed a significant difference in the mean slope values of wound healing between treatment and control groups.•Wound healing occurred faster with red laser compared to blue and green lasers.

Background and objective: Many studies have demonstrated that low-level laser therapy (LLLT) can improve wound healing in non-diabetic and diabetic animals. We compared the effects of red, green, and blue lasers in terms of accelerating oral wound healing in diabetic rats. Material and methods: Diabetes was successfully induced in 32 male Wistar rats using intraperitoneal injection of Streptozotocin (150 mg/kg). After intraperitoneal injection of the anesthetic agent, a full-thickness oral wound (10 mm × 2 mm) was created aseptically with a scalpel on hard palate of the diabetic rats. The study was performed using red (630 nm), green (532 nm), and blue (425 nm) lasers and a control group. We used an energy density of 2 J/cm2 and a treatment schedule of 3 times/week for 10 days. The area of wounds was measured and recorded on a chart for all rats. On the 10th day, the samples were then sacrificed and a full-thickness sample of wound area was prepared for pathological study. Results: We observed a significant difference (p < 0.001) in the mean slope values of wound healing between treatment and control groups. Moreover, the mean slope of wound healing differed significantly between red laser and two other lasers – blue and green (p < 0.001). The mean slopes of wound healing were not significantly different between blue laser and green laser (p = 0.777). Conclusion: The results of the present study provide evidence that wound healing is slower in control rats compared to the treatment groups. Moreover, the findings suggest that wound healing occurs faster with red laser compared to blue and green lasers.

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The effect of red, green and blue lasers on healing of oral wounds in diabetic rats
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 148, July 2015, Pages 242–245
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us