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Photodynamic activity of nanostructured fabrics grafted with xanthene and thiazine dyes against opportunistic fungi

Paper ID Volume ID Publish Year Pages File Format Full-Text
30026 44454 2015 10 PDF Available
Title
Photodynamic activity of nanostructured fabrics grafted with xanthene and thiazine dyes against opportunistic fungi
Abstract

•We produced antifungal nanostructured fabric using photosensitizers.•Antifungal activities examined via microdilution, zero zones, and quantitative assay.•In order to compare the inhibition rate among variables, we built Eq. (2).•The antifungal activities results in the order of AA < TBO < PB < RB.

Fungi are an important class of human pathogens for which considerable research has gone into defeating them. The photodynamic effects of rose bengal (RB), phloxine B (PB), azure A (AA), and toluidine blue O (TBO) dyes to inhibit Aspergillus fumigatus, Aspergillus niger, Trichoderma viride, Penicillium funiculosum, and Chaetomium globosum were investigated grafted to nano- and micro-structured fabrics. Three antifungal tests conducted: broth microdilution test of free dyes, zone of inhibition and quantitative antifungal assays on fabrics grafted with dyes. In the broth microdilution test, free RB displayed the lowest MIC at 32 μM to inhibit visible hyphal growth and germination but the antifungal ability of MIC for other photosensitizers below 63 μM was insignificant. RB and PB showed lower MIC than AA and TBO. In the inhibition zone tests, nanostructured fabrics grafted with RB and PB did not display fungal growth on the surface. Most microstructured fabrics grafted with AA and TBO showed little inhibition. In quantitative antifungal assay, nanostructured fabrics grafted with RB has the largest inhibition rate on T. viride and the lowest inhibition rate on P. funiculosum and the results showed the increasing inhibition rate in the order of AA < TBO < PB < RB.

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Photodynamic activity of nanostructured fabrics grafted with xanthene and thiazine dyes against opportunistic fungi
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 150, September 2015, Pages 50–59
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us