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Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits

Paper ID Volume ID Publish Year Pages File Format Full-Text
30779 44502 2011 4 PDF Available
Title
Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits
Abstract

Allergic rhinitis is a high-incidence allergic inflammation of the nasal airways that impacts quality of life. Of the numerous therapies used to treat allergic rhinitis, intranasal phototherapy has emerged as a promising new treatment modality for inflammatory airway disease. Phototherapy is widely used for the treatment of immune-mediated skin diseases because its profound immunosuppressive effect inhibits hypersensitivity reactions in the skin. Intranasal phototherapy using a combination of Ultraviolet-A (UVA) and Ultraviolet-B (UVB) plus Visible light (VIS) has been shown to suppress the clinical symptoms of allergic rhinitis, but limited data regarding its adverse effects on the nasal mucosa currently exists. In this study, we demonstrate that UV displays no harmful effects on the nasal mucosa cells of rabbits following 2 weeks of intranasal phototherapy.

► Intranasal phototherapy has been shown to suppress the symptoms of allergic rhinitis. ► The effect of intranasal phototherapy on the nasal mucosa of rabbits was assessed. ► A pathological change was not evident in the rabbit nasal mucosa or concha epithelium cells of the rabbit.

Keywords
Rhinophototherapy; Rabbits; Allergic rhinitis; Ultraviolet radiation
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Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 105, Issue 1, 5 October 2011, Pages 94–97
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us