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Dermatologic management, sun avoidance and vitamin D status in organ transplant recipients (OTR)

Paper ID Volume ID Publish Year Pages File Format Full-Text
30865 44510 2010 10 PDF Available
Title
Dermatologic management, sun avoidance and vitamin D status in organ transplant recipients (OTR)
Abstract

It is well known that skin cancer, especially cutaneous squamous cell carcinoma (SCC), in organ transplant recipients (OTRs) has higher incidence rates, behaves more aggressively and has higher rates of metastasis. OTRs who have been treated for many years with immunosuppressive medication are at the highest risk for developing malignant skin tumors. Protection against solar and artificial UV-radiation is crucial to prevent skin cancer in OTRs. However, investigations have revealed that solar UV-B-exposure and serum 25(OH)D levels positively correlate with decreased risk for various internal malignancies (e.g. breast, colon, prostate, and ovarian cancer) and other severe diseases. Therefore, it is important to detect and treat vitamin D deficiency in OTRs. This review discusses guidelines for the optimal management of these patients, that require communication between the transplant teams, the treating dermatologist and other clinicians.

Keywords
Cancer protection; Organ transplant recipients; Skin cancer; Solar UV-exposure; UV-protection; Vitamin D deficiency
First Page Preview
Dermatologic management, sun avoidance and vitamin D status in organ transplant recipients (OTR)
Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 101, Issue 2, 3 November 2010, Pages 150–159
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering