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Preparation and biological activity of novel cucurbit[8]uril–fullerene complex

Paper ID Volume ID Publish Year Pages File Format Full-Text
31192 44564 2006 5 PDF Available
Title
Preparation and biological activity of novel cucurbit[8]uril–fullerene complex
Abstract

The synthesis of a novel cucurbit[8]uril(CB8)–fullerene[60] supramolecular complex using a simple and efficient pathway is reported for the first time. In the complex, which was found to be of the 1:2 type, the compounds interact weekly with each other. The complex was characterized by UV/Vis, FTIR, elemental analysis, X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). TEM analysis shows that the average particle diameter is about 19 nm. The in vitro antitumour activity of the complex has been tested and the result shows that the complex exhibits better antitumour activity against HeLa cells. The antitumour mechanism of the complex was investigated for the first time.

Keywords
Fullerene complex; C60; Cucurbit[8]uril; Solvent free; Antitumour activity
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Preparation and biological activity of novel cucurbit[8]uril–fullerene complex
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 85, Issue 3, 1 December 2006, Pages 223–227
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
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