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In situ patterning and controlling living cells by utilizing femtosecond laser

Paper ID Volume ID Publish Year Pages File Format Full-Text
31249 44718 2016 28 PDF Available
Title
In situ patterning and controlling living cells by utilizing femtosecond laser
Abstract

•Photoinduced surface modification for cell patterning and controlling is summarized.•Femtosecond laser ablation enables precise living cell patterning.•Plural living cells are arbitrarily patterned by femtosecond laser ablation.•Cell-cell connection is demonstrated by femtosecond laser ablation.•Cell migration is spatio-temporally controlled by femtosecond laser ablation.

Photo-induced processes have high potential in in situ patterning and controlling living cells, whose developments are introduced and recent progresses by utilizing femtosecond laser are described. Photochemical and photothermal surface modification performed by conventional light and nanosecond laser irradiation is summarized and their applicability is considered. Femtosecond laser ablation has superior features due to its photomechanical mechanism, which is confirmed by ultrafast spectroscopy and imaging of a model film under laser ablation. Femtosecond laser ablation of physiological solutions generates shockwave and cavitation bubbles, which is employed for patterning and manipulating living cells. Femtosecond laser ablation fabricating cytophobic and cytophilic domains enable us to form living cell patterns and to study cell migration and cell–cell interaction. Finally summary and perspective are presented.

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Keywords
Femtosecond laser cavitation; Femtosecond laser ablation; Living cell manipulation; Living cell patterning; Cell-cell interaction; Cell migration
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In situ patterning and controlling living cells by utilizing femtosecond laser
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology C: Photochemistry Reviews - Volume 28, September 2016, Pages 1–28
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us